Molecular genotyping to differentiate endogenous reactivation and exogenous reinfection of recurrent tuberculosis
نویسندگان
چکیده
منابع مشابه
Recurrent Tuberculosis and Exogenous Reinfection, Shanghai, China
Of 52 patients with recurrent tuberculosis in Shanghai, People's Republic of China, 32 (61.5%) had isolates in which genotype patterns of Mycobacterium tuberculosis differed between first and second episodes. This result indicates that exogenous reinfection is common in an area with a high incidence of tuberculosis.
متن کاملA model for tuberculosis with exogenous reinfection.
Following primary tuberculosis (TB) infection, only approximately 10% of individuals develop active T.B. Most people are assumed to mount an effective immune response to the initial infection that limits proliferation of the bacilli and leads to long-lasting partial immunity both to further infection and to reactivation of latent bacilli remaining from the original infection. Infected individua...
متن کاملAIDS pacient's long-term battle with multiply recurrent tuberculosis: reinfection or reactivation?
The advent of Mycobacterium tuberculosis strain genotyping has allowed differentiation between disease relapse and exogenous re-infection. We report here a remarkable case of multiply recurrent tuberculosis in a patient living with HIV. Between 1995 and 2009, a young HIV-infected intravenous drug user, who was reluctant to comply with anti-retroviral treatment, underwent at least five tuberculo...
متن کاملIncident Tuberculosis among Recent US Immigrants and Exogenous Reinfection
Mathematical models and molecular epidemiologic investigation support the argument that exogenous reinfection plays an important role in tuberculosis transmission in high-incidence regions. We offer additional data from tuberculosis cases among recent US immigrants which strengthen the claim that reinfection in areas of intense transmission is common.
متن کاملMolecular epidemiology study of exogenous reinfection in an area with a low incidence of tuberculosis.
In geographical areas with a low incidence of tuberculosis, recurrent tuberculosis is generally due to reactivation of the disease. However, the relative contribution of tuberculosis reinfection increases in parallel with the incidence of disease and is likely to depend on the epidemiological context: factors such as the spread of multidrug resistance, human immunodeficiency virus (HIV) infecti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
سال: 2018
ISSN: 2405-5794
DOI: 10.1016/j.jctube.2018.10.001